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James LaBelle, MD

Assistant Professor of Pediatrics

LaBelle

James LaBelle, MD, PhD, provides care for children of all ages with cancer and blood diseases, including leukemia and lymphoma. In particular, Dr. LaBelle specializes in stem cell transplantation, replacing a patient's diseased bone marrow and immune system with healthy cells.

Dr. LaBelle's laboratory research focuses on understanding at a molecular level the reason why some pediatric cancers are resistant to therapy. He currently serves as the primary investigator on a study examining a critical network of proteins that regulate whether a malignant cell lives or dies. The normal signaling between these proteins often is disturbed in cancerous cells. Through this research, he hopes to identify novel cell death regulatory mechanisms in resistant hematopoietic malignancies and design effective strategies to overcome them. Dr. LaBelle's research is currently funded by the National Institutes of Health.

A dedicated mentor, Dr. LaBelle also received special recognition for teaching medical students, residents, and fellows about pediatric hematology, oncology, and hematopoietic stem cell transplantation.

 


Related Videos

Why Should Referring Physicians Chose University of Chicago? Video

Why Should Referring Physicians Chose University of Chicago?

Dr. James LaBelle, assistant professor of pediatrics, explains how his team works in collaboration with referring physicians to provide the best possible care for patients.

Future of Stem Cell Transplant Departments Video

Future of Stem Cell Transplant Departments

Dr. James LaBelle, assistant professor of pediatrics, explains why the stem cell transplant departments are uniquely positioned to make major advances in the area of small molecule targeted therapeutics.

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Dr. James LaBelle, assistant professor of pediatrics, is focusing his research on using parts of natural proteins to induce cell death in cancers that are completely refractory to conventional chemotherapy.

Technological Advances at University of Chicago Video

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Dr. James LaBelle, assistant professor of pediatrics, describes how transplantation works as an immunomodulatory tool.

Dr. James LaBelle Video

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Dr. James LaBelle, assistant professor of pediatrics, says the collaborative approach to cancer care and the ability to execute stem cell transplantation are what makes his department unique.

Transplants for Pediatric Leukemia Video

Transplants for Pediatric Leukemia

Dr. James LaBelle, assistant professor of pediatrics, takes an in-depth look at acute lymphoblastic leukemia, including whether or not timing and site relapse matters for HSCT and transplant compared to chemotherapy in CR2. Dr. LaBelle ...

Stem Cell Transplant Methodology Video

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Dr. James LaBelle, assistant professor of pediatrics, discusses stem cell source, allogeneric HSCT and HLA typing. Dr. LaBelle also explains donor selection, transplanting the graft and post-transplant care.


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